MTHFR Genetic Test
The MTHFR Genetic Test looks for two common gene changes, C677T and A1298C, that affect how your body uses folate, a critical B vitamin. The MTHFR protein helps your body process folate and break down the amino acid homocysteine. Testing can reveal if these gene variants are contributing to elevated homocysteine levels in your blood. For individuals prescribed methotrexate, test results can also help providers determine a safer, more appropriate dosage. While medical experts generally prioritize homocysteine levels, knowing your MTHFR status can offer relevant personal health insights.
Self-Pay Price Comparison
| Provider | Price | vs. Highest | Order |
|---|---|---|---|
Quest QuestHealth self-pay | Not Available | N/A | Check Provider Site · Quest |
LabCorp Labcorp OnDemand | Not Available | N/A | Check Provider Site · LabCorp |
GoodLabs Discount lab network | $128.00Best value | Best price | Order · GoodLabs |
What This Test Measures
Key analytes included in this test (see your lab’s order for the full finalized list).
MTHFR C677T and A1298C genotyping. Variants reduce methylenetetrahydrofolate reductase activity, impairing one-carbon metabolism and potentially elevating homocysteine.