LabReconTestsGeneralMTHFR Genetic Test
GeneralPrices verified 2026-03-23

MTHFR Genetic Test

The MTHFR Genetic Test looks for two common gene changes, C677T and A1298C, that affect how your body uses folate, a critical B vitamin. The MTHFR protein helps your body process folate and break down the amino acid homocysteine. Testing can reveal if these gene variants are contributing to elevated homocysteine levels in your blood. For individuals prescribed methotrexate, test results can also help providers determine a safer, more appropriate dosage. While medical experts generally prioritize homocysteine levels, knowing your MTHFR status can offer relevant personal health insights.

Quest
Not Available
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LabCorp
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GoodLabs
$128
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Cost Recon

Self-Pay Price Comparison

ProviderPricevs. HighestOrder
Quest
QuestHealth self-pay
Not AvailableN/ACheck Provider Site · Quest
LabCorp
Labcorp OnDemand
Not AvailableN/ACheck Provider Site · LabCorp
GoodLabs
Discount lab network
$128.00Best valueBest priceOrder · GoodLabs
About GoodLabs: About GoodLabs: GoodLabs offers the same Quest and LabCorp tests at discounted self-pay rates. Their prices reflect direct negotiated rates; not retail list prices.
Recon Snapshot

What This Test Measures

Key analytes included in this test (see your lab’s order for the full finalized list).

MTHFR C677T
MTHFR A1298C
Clinical Notes

MTHFR C677T and A1298C genotyping. Variants reduce methylenetetrahydrofolate reductase activity, impairing one-carbon metabolism and potentially elevating homocysteine.